Antineutrophil Cytoplasmic Antibody and Multiple Sclerosis

The antineutrophil cytoplasmic antibody-associated vasculitides.

Wegener's granulomatosis, microscopic polyangiitis, and Churg-Strauss syndrome are small- to medium-vessel vasculitides linked by overlapping pathology and the presence of antineutrophil cytoplasmic antibodies (ANCA). Commonly referred to as the ANCA-associated vasculitides, these diseases are challenging to diagnose and to treat. Distinguishing the ANCA-associated vasculitides from other forms...

Treatment of antineutrophil cytoplasmic antibody-associated vasculitis.

PURPOSE OF REVIEW The primary idiopathic small-vessel vasculitis syndromes include granulomatosis with polyangiitis, Churg-Strauss syndrome, and microscopic polyangiitis. These disorders are commonly referred to as antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides and prominently affect the pulmonary vasculature. Although significant progress has been made in the management of ...

Ocular manifestations of the antineutrophil cytoplasmic antibody and antiphospholipid syndromes

Sir, I would like to correct my comment in my original letter,[1] commenting on the article published by Rishi et al.,[2] which is “ this condition is unlikely to occur on ground of embryology, as the central retinal artery develops from a single hyaloid artery and enters the lamina cribrosa.” Now, my attention has been drawn by Dr. S S Hayreh that on certain occasions it is possible to have tw...

Necrotizing and crescentic lupus nephritis with antineutrophil cytoplasmic antibody seropositivity.

BACKGROUND AND OBJECTIVES Lupus nephritis is a classic immune complex glomerulonephritis. In contrast, antineutrophil cytoplasmic antibodies are associated with necrotizing and crescentic glomerulonephritis, in the absence of significant immune deposits. Antineutrophil cytoplasmic antibodies are detected by indirect immunofluorescence in 20% of patients with systemic lupus erythematosus. We rep...

Antineutrophil cytoplasmic antibody-positive digital necrosis in a patient with limited systemic sclerosis.